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MAINTAIN: Phase II Study of Switching ET ± Ribociclib for HR+/HER2- Metastatic Breast Cancer After Failure of Previous ET + CDK4/6i

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Ribociclib combined with switching endocrine therapy improved PFS in patients with HR-positive/HER2-negative metastatic breast cancer who progressed on prior standard of care CDK4/6 inhibition with endocrine therapy.

Released: June 09, 2022

Expiration: June 08, 2023

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Supported by educational grants from

AbbVie

AstraZeneca

Bristol Myers Squibb

Daiichi Sankyo, Inc.

Gilead Sciences, Inc.

GlaxoSmithKline

Jazz Pharmaceuticals, Inc.

Merck Sharp & Dohme Corp.

Novartis Pharmaceuticals Corporation

Seagen and Genmab