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Phase III OlympiA: Interim Analysis of Adjuvant Olaparib vs Placebo in BRCA-Mutated, HER2-Negative, High-Risk Early Breast Cancer

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In this prespecified interim analysis of patients with germline BRCA1/2-mutated, HER2-negative early breast cancer at high risk of recurrence, adjuvant olaparib for 1 year significantly improved invasive and distant disease–free survival vs placebo.

Released: June 09, 2021

Expiration: June 08, 2022

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Supported by educational grants from

AbbVie

Amgen, Inc.

AstraZeneca

Bristol Myers Squibb

Daiichi Sankyo, Inc.

Exelixis

Gilead Sciences, Inc.

GlaxoSmithKline

Ipsen Biopharmaceuticals Inc

Merck Sharp & Dohme Corp.

Novartis Pharmaceuticals Corporation

Pfizer, Inc.

Pharmacyclics LLC an AbbVie Company and Janssen Biotech Inc

Sanofi Genzyme