Antidepressants in Bipolar Disorder
What Is the Role for Antidepressants in Bipolar Disorder?

Released: October 05, 2021

Expiration: October 04, 2022

Joseph F Goldberg
Joseph F Goldberg, MD
Greg W. Mattingly
Greg W. Mattingly, MD

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In this episode, Joseph Goldberg, MD, and Greg Mattingly, MD, discuss the role of antidepressants in bipolar disorder. They review use of newer antidepressants (eg, vortioxetine, vilazodone) for bipolar depression despite lack of large, formal studies for that indication, the safety/efficacy of antidepressants for bipolar II vs bipolar I, antidepressant monotherapy in bipolar II depression, ketamine/esketamine for bipolar depression, and discuss the role for an antidepressant for bipolar depression in the absence of mixed features.