Podcast: HIV Novel Therapies
Key Decisions in HIV Care: Considering Novel Therapies for HIV

Released: May 02, 2022

Expiration: May 01, 2023

William R. Short
William R. Short, MD, MPH, FIDSA

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In this episode from the series “Key Decisions in HIV Care,” Cristina Mussini, MD, and William R. Short, MD, MPH, AAHIVS, discuss novel therapies for HIV prevention and treatment, including:

  • Prevention
    • Cabotegravir for pre-exposure prophylaxis (PrEP) with the latest results from the HPTN 083 and HPTN 084 studies
    • Novel PrEP therapies in development, including islatravir and lenacapavir
  • Initial therapy
    • Lenacapavir for initial therapy with results from the CALIBRATE study
  • Switch strategies
    • Cabotegravir as a switch strategy with the latest results from the ATLAS-2M study, evaluating Q4W vs Q8W dosing, data on direct-to-inject without the oral lead-in, and data to date in pregnancy
  • Heavily treatment–experienced patients
    • Currently available novel therapies for heavily treatment–experienced patients, including fostemsavir and ibalizumab
    • Lenacapavir for heavily treatment–experienced patients with results from the CAPELLA stud