2017 American Society of Hematology Annual Meeting

December 9-12, 2017; Atlanta, Georgia
This program provides coverage of the 2017 ASH annual meeting with summary slidesets and expert analyses of key results on hematologic malignancies, including lymphomas/CLL, leukemias, multiple myeloma, and novel targeted therapies, as well as on nonmalignant hematologic disorders.

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Program Content

Activities

Key Studies ASH 2017
Preview of ASH 2017: Key Expert-Selected Studies
Clinical Thought
Conference Coverage
Congratulations: You achieved a completion on 04/09/2022

Released: December 06, 2017

Activities

Ibrutinib in R/R MCL
Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma: 3.5-Year Follow-up of a Pooled Analysis of 3 Clinical Trials
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 13, 2017

First-line Len + Ritux in MCL
Extended Follow-up of Mantle Cell Lymphoma Patients Treated With First-line Lenalidomide + Rituximab
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

Acalabrutinib in R/R MCL
ACE-LY-004: Phase II Trial of BTK Inhibitor Acalabrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 11, 2017

JCAR017 in R/R NHL
CAR T-Cell Therapy JCAR017 in R/R DLBCL From TRANSCEND NHL 001: Correlation Between Patient Characteristics and Clinical Outcomes
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 20, 2017

R/R DLBCL: Polatuzumab Vedotin
Randomized Phase II Trial of Polatuzumab Vedotin Addition to Bendamustine + Rituximab in Patients With R/R DLBCL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

R/R HCL: Vemurafenib + Rituximab
HCL-PG03: Phase II Trial of Vemurafenib + Rituximab in Patients With Relapsed/Refractory Hairy Cell Leukemia
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 11, 2017

R/R CLL: Ibrutinib + Venetoclax
CLARITY: Feasibility Study of Combination Ibrutinib + Venetoclax in R/R CLL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 19, 2017

CLL: Venetoclax + Ibrutinib
Phase II Trial of Venetoclax + Ibrutinib in Patients With Relapsed/Refractory or Untreated High-Risk CLL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2017

MAINTAIN: BR + Ritux Maint in FL
Phase III MAINTAIN: Extended Rituximab Maintenance in Follicular Lymphoma After First-line Bendamustine + Rituximab
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 20, 2017

JULIET: CART in R/R DLBCL
JULIET: Phase II Primary Analysis of CAR T-Cell Therapy Tisagenlecleucel in Adult Patients With Relapsed/Refractory DLBCL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

R/R cHL: BV + Nivolumab
Phase I/II Study of Brentuximab Vedotin + Nivolumab for Patients With R/R Classical Hodgkin Lymphoma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2017

Nivolumab After PD in R/R cHL
Analysis of Nivolumab Continued Beyond Progression in Patients With R/R Classical Hodgkin Lymphoma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

Brentuximab Vedotin + AVD in cHL
ECHELON-1: Phase III Trial of First-line Brentuximab Vedotin + AVD Chemotherapy in Advanced Classical Hodgkin Lymphoma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

MURANO: VEN + R in R/R CLL
MURANO Interim Analysis: Venetoclax + Rituximab vs Bendamustine + Rituximab in Patients With Relapsed/Refractory CLL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

Activities

Inotuzumab + Bosutinib
Interim Report: Inotuzumab Ozogamicin + Bosutinib in R/R Ph+ ALL or CML in Lymphoid Blast Phase
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2017

Midostaurin Maintenance
Midostaurin Maintenance After Midostaurin Plus Chemotherapy in FLT3-Mutated AML: Post Hoc Analysis in RATIFY
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 13, 2017

EURO-SKI: TKI Cutoffs in CML
EURO-SKI: Defining Cutoffs for Tyrosine Kinase Inhibitor Cessation in Patients With Chronic Myeloid Leukemia
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2017

HOVON97: Azacitidine Maint
Phase III HOVON97: Azacitidine Maintenance in Older Patients With AML and Refractory Anemia
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2017

RATIFY: <i>NPM1</i> and <i>FLT3</i>
Prognostic Role of NPM1/FLT3-ITD Genotypes in AML: Analysis of the RATIFY Trial
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

Gilteritinib in ND AML
Gilteritinib With Induction and Consolidation Chemotherapy for Newly Diagnosed AML: Preliminary Phase I Results
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 13, 2017

Ivosidenib in AML
Phase I Study: Ivosidenib (AG-120) in Mutant IDH1 Acute Myeloid Leukemia and Other Advanced Hematologic Malignancies
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 20, 2017

mIDH Inhibition in AML
Phase I Study: Ivosidenib or Enasidenib + Standard Induction Chemotherapy in Newly Diagnosed AML With IDH1/IDH2 Mutations
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

Nivolumab + IA in AML
Phase II Study: Frontline Cytarabine and Idarubicin + Nivolumab in Newly Diagnosed AML
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 19, 2017

Venetoclax + LDAC in AML
Phase I/II Study of Venetoclax + Low-Dose Cytarabine in Untreated, Elderly Patients With AML: Outcomes at 1 Year
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2017

CPX-351 in High-Risk AML
CPX-351 in Patients With Newly Diagnosed AML at High Risk for Induction Mortality: Initial Phase II Results
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2017

Nilotinib + PegIFN in CP CML
Phase III PETALs Interim Analysis: Nilotinib ± PegIFN alfa-2a in Patients With Newly Diagnosed Ph-Positive CP CML
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 19, 2017

Ponatinib + Steroids in Ph+ ALL
GIMEMA LAL1811: Phase II Study of Frontline Ponatinib + Steroids in Elderly or Unfit Patients With Ph+ ALL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 20, 2017

NGS for MRD in AML
Prospective Molecular MRD Detection in AML by Next-Generation Sequencing
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

Activities

EMN02/HO95: Double vs Single ASCT
Double Vs Single ASCT in Newly Diagnosed Multiple Myeloma: An Analysis of the EMN02/HO95 Phase III Trial
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

GEM-CESAR: KRD + ASCT in SMM
Phase II GEM-CESAR: KRd + ASCT in High-Risk Smoldering Myeloma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2017

BCMA-CART in R/R MM
BCMA-Targeted CAR T-Cells ± Cyclophosphamide in Relapsed/Refractory Multiple Myeloma: Phase I Study
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2017

CD19/BCMA CAR T-cells
Pilot Study: Combined CD19- and BCMA-Targeted CAR T-Cells in Relapsed/Refractory Myeloma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

CENTAURUS: Dara in SMM
CENTAURUS: Randomized Study of Daratumumab Dosing in Intermediate- or High-Risk Smoldering Multiple Myeloma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

POLLUX Follow-up
Daratumumab + Rd vs Rd Alone in Relapsed/Refractory Myeloma: Extended Follow-up From POLLUX
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 19, 2017

Anti-BCMA CART in RRMM
bb2121 Anti-BCMA CAR T-Cell Therapy in Relapsed/Refractory Myeloma: Updated Phase I Results
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 14, 2017

MCARH171 CAR T-Cells in MM
Phase I Study: MCARH171 BCMA-Targeted CAR T-Cells in Advanced Multiple Myeloma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

IFM 2013-01: PCD in RR MM
Phase II IFM 2013-01: Pomalidomide/Cyclophosphamide/Dexamethasone in Relapsed Multiple Myeloma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2017

Phase Ib Pavo: SC Dara in R/R MM
Phase Ib PAVO: Subcutaneous Administration of Coformulated Daratumumab + rHuPH20 in Relapsed/Refractory Myeloma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

LEN-ELO Maintenance for MM
Elotuzumab/Lenalidomide/Dexamethasone Maintenance After ASCT in Patients With MM: Preliminary Results From a Phase II Study
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2017

MM: Ixazomib Maintenance
Long-term Ixazomib Maintenance in ASCT-Ineligible Patients With Newly Diagnosed MM: Pooled Analysis of 4 Phase I/II Trials
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2017

ALCYONE: Dara + VMP
ALCYONE: Daratumumab Plus VMP vs VMP Alone in Newly Diagnosed, Transplantation-Ineligible Myeloma
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 13, 2017

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Activities

Brentuximab Vedotin in CTCL
Extended Follow-up From the ALCANZA Phase III Trial of Brentuximab Vedotin vs Methotrexate or Bexarotene for Previously Treated CD30-Positive CTCL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 20, 2017

Avapritinib in Advanced Systemic Mastocytosis
Phase I Study of KIT D816V Inhibitor Avapritinib (BLU-285) in Advanced Systemic Mastocytosis
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 20, 2017

Avadomide (CC-122) + Obinutuzumab in R/R NHL
Phase Ib Study: Avadomide (CC-122) Plus Obinutuzumab in Relapsed/Refractory B-Cell NHL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2017

ACE-CL-003: Acalabrutinib + Obinutuzumab in CLL
ACE-CL-003: Phase Ib/II Study of Acalabrutinib + Obinutuzumab in Patients With Untreated or R/R CLL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2017

MAVORIC: Mogamulizumab in CTCL
Phase III MAVORIC: Mogamulizumab vs Vorinostat in Patients With Previously Treated CTCL
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 19, 2017

HERCULES: Caplacizumab in aTTP
HERCULES: Caplacizumab in Adult Patients With Acquired Thrombotic Thrombocytopenic Purpura
Conference Coverage
Slideset Download
Congratulations: You achieved a completion on 04/09/2022

Released: December 19, 2017

Faculty

cover img faculity

Christopher W. Ryan, MD

Assistant Professor of Medicine
Division of Hematology & Medical Oncology
Oregon Health and Science University
Portland, Oregon

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Supporters

This activity is supported by educational grants from

AbbVie

AstraZeneca

Celgene

Genentech TEXT Only

Janssen Biotech Pharmacyclics Abbvie

Jazz Pharmaceuticals, Inc.

Novartis Pharmaceuticals Corporation

Pharmacyclics Inc

Seagen

Takeda Oncology